Lance A. Johnson, PhD
Connect
859-323-2746Johnson.Lance@uky.edu
Positions
- Associate Professor
- Director of Graduate Studies, Department of Physiology
College Unit(s)
Other Affiliation(s)
- Nutritional Sciences Graduate Faculty
Biography and Education
Education
Postdoctoral, Behavioral Neuroscience, Oregon Health & Science University
PhD, Molecular & Cellular Pathology, University of North Carolina
BA, Journalism & Mass Communication, University of North Carolina
Research
Research in our lab is dedicated to understanding the role of the Alzheimer's disease risk factor Apolipoprotein E (APOE) in cerebral metabolism. With a special focus on glia and their contributions to neurodegeneration, we employ a variety of transcriptomic and metabolomic approaches (from cells to mice to humans) in order to identify early-life changes in metabolism associated with APOE. Our lab's overarching goal is to discover new therapeutic targets that will allow us to reprogram metabolism in individuals at-risk for Alzheimer's disease in order to enhance cognitive resilience and to extend the brain’s health span.